The Shadow Walkers is the suspenseful story of a group of lab technicians and military personnel who awaken in a subterranean laboratory with no memory of who they are. They quickly discover that they are sealed in, with only one way to get out alive. They struggle through the darkness to find the escape tunnel that leads to the surface, pursued by mutated creatures that stalk them from the shadows. Risking death with every turn, they begin to regain their memories, discovering the origin of the deadly creatures and the part they played in their creation.