Woody Harrelson and Antonio Banderas star as best friends and professional boxing rivals Vince Boudreau and Caesar Dominguez, both of whom haven't worked in years. Finally, from out of the blue, they get the chance of a lifetime: an assignment to work together in Vegas. The job promises big money, but there's a hitch: They have to be there NOW. They quickly hit the road with Grace Pasic (Lolita Davidovich) at the wheel, embarking on a circuitous route through the sizzling desert. Sparks fly as the competitive Vince and Caesar antagonize each other to a frenzy, matched only by Grace's own combative temper. The going gets rougher when they pick up sultry hitchhiker Lia (Lucy Liu), whose presence throws the trio into further upheaval. A riotous race ensues as Vince and Caesar scramble to make it to Vegas for their big showdown.