Game Boy Advance players take control of the Disney title duo to embark on a side-shooting, platform-hopping, action-puzzle-solving quest to rescue Nani and David, who have been kidnapped by the nefarious Hamsterviel. The game features 29 levels in all, in which players control both the little island girl and her extraterrestrial friend. To slow the two down, the villain has unleashed a number of "experiments" (like Stitch himself) in their path. Luckily, Stitch can harness the powers of these other experiment creatures, and make creative use of the borrowed abilities to overcome tricky obstacles.