One year after the events of "Kickboxer: Vengeance", Kurt Sloan has vowed never to return to Thailand. However, while gearing up for an MMA title shot, he finds himself sedated and forced back into Thailand, this time in prison. He is there because the ones responsible want him to face a 6'8" 400 lbs. beast named Mongkut and in return for the fight, Kurt will get two million dollars and his freedom back.