White Girl is a twisted teenage prostitute with a bad attitude and a nasty eating disorder, who's been sent to the slammer for 25 years. Her cellmate, Cyclona, is equally deranged, being a vicious killer. And, as like minds attract, the two are quick to form a truly twisted alliance. When the opportunity arises, White Girl and Cyclona manage to escape from the pen and embark on a non-stop orgy of violence and debauchery, all while hoping to make it across the border into Mexico in order to seek refuge with Cyclona's proxy caretaker, Sister Gomez. However, there's a big hitch in their plans as the good Sister isn't as "she" seems...