The reserved Lauren (played by Lauren Anne Miller) and the irrepressible Katie (Ari Graynor) are polar opposites... and past enemies. But when both come up short on the funds needed to afford their dream New York City apartment a mutual friend (Justin Long) re-introduces them and they reluctantly agree to room together. These apartment-mates have nothing in common - until Lauren discovers that Katie is working as a phone-sex operator, and recognizes a good business opportunity. But as their business partnership takes off, their new found friendship finds unexpected challenges that may leave them both, as they say, hanging on the telephone.